Among those killed is a 16-year-old boy, 17-year-old girl and a 14-year-old girl, while those injured include one teacher and seven students from Oxford High School in Oxford, Michigan.
Two of the injured are currently in hospital undergoing surgery for serious injuries while the other six are believed to be in stable condition.
After initially opening fire, police were quick to apprehend the shooter.
The motive behind the shooting is still unclear to authorities who are continuing to investigate.
Undersheriff Michael McCabe addressed reporters at the scene saying the entire shooting was extremely quick and resulted in the suspect being arrested after first firing off around 20 shots.
“The whole thing lasted five minutes," he said.
The suspect is not cooperating with police after demanding a lawyer shortly after his arrest on the advice of his parents.
As one of many. School shooting across the US, the incident is likely to spark further debate on current US gun laws.
Stay up-to-date on the latest news with Your Morning Agenda - supported by a network of local journalists from all major Australian cities, ensuing timely and first hand insights on local stories:
Download LiSTNR and enjoy a new world of audio. All your favourite shows and stations in one library.